Antonym of to be of no consequence

Antonym of small Antonym of trivial Antonym of low Antonym of light Antonym of minute Antonym of little Antonym of irrelevant Antonym of weak Antonym of humble Antonym of insignificant Antonym of secondary Antonym of extraneous Antonym of petty Antonym of obscure Antonym of minor Antonym of paltry Antonym of measly Antonym of narrow Antonym of remote Antonym of fine Antonym of slight Antonym of trifling Antonym of thin Antonym of modest Antonym of pitiful Antonym of inconsequential Antonym of neither here nor there Antonym of sorry Antonym of superficial Antonym of meaningless Antonym of brief Antonym of meager Antonym of surface level Antonym of lightweight Antonym of scanty Antonym of negligible Antonym of cramped Antonym of mere Antonym of worthless Antonym of slender Antonym of peripheral Antonym of limited Antonym of inadequate Antonym of minuscule Antonym of null Antonym of futile Antonym of imperceptible Antonym of abstract Antonym of inadmissible Antonym of diminutive Antonym of tiny Antonym of sordid Antonym of ignorable Antonym of vain Antonym of senseless Antonym of wee Antonym of infinitesimal Antonym of metaphysical Antonym of short Antonym of piddling Antonym of imponderable Antonym of puny Antonym of frivolous Antonym of petite Antonym of foreign Antonym of baby Antonym of insubstantial Antonym of unnecessary Antonym of no account Antonym of intangible Antonym of marginal Antonym of nonessential Antonym of immature Antonym of inessential Antonym of unrelated Antonym of nominal Antonym of airy Antonym of pocket Antonym of unconnected Antonym of miniature Antonym of outside Antonym of nonexistent Antonym of confined Antonym of dinky Antonym of dispensable Antonym of dreamy Antonym of lesser Antonym of unimposing Antonym of expendable Antonym of least Antonym of spiritual Antonym of dwarf Antonym of teeny Antonym of unneeded Antonym of inapplicable Antonym of second Antonym of mental Antonym of inconsiderable Antonym of smallish Antonym of restricted Antonym of psychic Antonym of inappreciable Antonym of unreal Antonym of stunted Antonym of weightless Antonym of off Antonym of undersized Antonym of unessential Antonym of incorporeal Antonym of ungenerous Antonym of piffling Antonym of pocket sized Antonym of astral Antonym of elf Antonym of single story Antonym of pettifogging Antonym of teeny weeny Antonym of fiddling Antonym of mild Antonym of mini Antonym of fractional Antonym of near to the ground Antonym of itsy bitsy Antonym of underdeveloped Antonym of small time Antonym of weeny Antonym of nonconcrete Antonym of weedy Antonym of peewee Antonym of footling Antonym of niggling Antonym of incommodious Antonym of bijou Antonym of pygmy Antonym of nugatory Antonym of psychical Antonym of exiguous Antonym of disembodied Antonym of low rise Antonym of poky